Microbiological profile of bacteremies and candidemies of community origin at the Mato Grosso do Sul hospital

Abstract

Introduction: Community infections, caused by antibiotic-resistant bacteria, are a potential problem, contributing to an increase in the morbidity and mortality rate of hospitalized patients. Objective: To describe the microbiological profile of bacteremia and candidemia of community origin, confirmed by blood culture at the Regional Hospital of Mato Grosso do Sul (HRMS) during the year 2017. Method: This is a cross-sectional descriptive study, through electronic records and records from the HRMS Microbiology Laboratory. BIOESTAT 5.0 software was used for statistical analysis, with a significance level of 5%. Results: We identified 52 patients with bacteremia of community origin, corresponding to 0.5% of all blood cultures performed and 4.21% of positive blood cultures in the year 2017. There was no significant difference between gender and age. 67.3% of the patients presented comorbidities, mainly cardiac and diabetes mellitus and / or obesity. Bloodstream infections were mostly primary, and gram-negative bacteria accounted for the majority of cases. Resistant microorganisms corresponded to 37.28% of all bacteria isolated, of which 6 were ESBL positive. No resistant yeasts were identified except Candida krusei with intrinsic resistance to fluconazole. Conclusion: Community infections identified in the year 2017 were mainly caused by gram-negative bacteria, with prevalence of profiles with sensitivity and affected patients over 60 years, who are more subject to complications and early evolution to death, especially diabetics and / or obese.